Now: Christina Applegate
Her world changed when she was diagnosed with breast cancer in 2008. When she found out she carried the BRCA1 gene, she underwent a mastectomy. We’re glad to hear she is healthy now!

Now: Christina Applegate
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Then: Marisa Tomei
This actress became popular during the early 90’s when she appeared in My Cousin Vinny. She even won the Academy Award for Best Supporting Actress for the role! Her appearance in A Different World, the spin-off for The Cosby Show, took her to new heights.

Then: Marisa Tomei